PREPARATION AND EVALUATION OF METRONIDAZOLE MATRIX TABLETS FOR COLON TARGETING
نویسندگان
چکیده
منابع مشابه
Formulation And Evaluation of Flurbiprofen Matrix Tablets For Colon Targeting
The present study is the development of colon targeted matrix tablets of the drug flurbiprofen, a NSAIDS of the class of Ibuprofen designed to prolonged the release for sustained effect. Different formulation (F1 TO F9) batches were made with the help of different polymers and their different proportions (Guar Gum, Eudragit RL, Eudragit RS ) with the help of Wet granulation techniques. The prep...
متن کاملMatrix-mini-tablets of lornoxicam for targeting early morning peak symptoms of rheumatoid arthritis
Objective(s): The aim of present research was to develop matrix-mini-tablets of lornoxicam filled in capsule for targeting early morning peak symptoms of rheumatoid arthritis. Materials and Methods:Matrix-mini-tablets of lornoxicam were prepared by direct compression method using microsomal enzyme dependent and pH-sensitive polymers which were further filled into an empty HPMC capsule. To asses...
متن کاملFormulation and Evaluation of Chondroitin Sulphate Tablets of Aceclofenac for Colon Targeted Drug Delivery
The aim of the present study was to develop a single unit, site-specific matrix tablets of aceclofenac allowing targeted drug release in the colon with a microbially degradable polymeric carrier, chondroitin suphate (CS) and to coat the optimized batches with a pH dependent polymeric. The tablets were prepared by wet granulation method using starch mucilage as a binding agent and HPMC K-100 ...
متن کاملPreparation and In vitro Investigation of Chitosan Compressed Tablets for Colon Targeting.
PURPOSE The aim of the present study was minimizing the drug release in upper gastro intestinal tract and targeting to colon by using the principles of compression coat. METHODS Compression coated tablets of Ibuprofen were prepared by direct compression method using chitosan (300, 250, 200 & 175 mg). Tablets were evaluated for their physicochemical properties and in vitro drug release studies...
متن کاملFormulation and Evaluation of Chondroitin Sulphate Tablets of Aceclofenac for Colon Targeted Drug Delivery
The aim of the present study was to develop a single unit, site-specific matrix tablets of aceclofenac allowing targeted drug release in the colon with a microbially degradable polymeric carrier, chondroitin suphate (CS) and to coat the optimized batches with a pH dependent polymeric. The tablets were prepared by wet granulation method using starch mucilage as a binding agent and HPMC K-100 ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: World Journal of Pharmaceutical Research
سال: 2017
ISSN: 2277-7105
DOI: 10.20959/wjpr20178-9122